Thermal Analysis of Whole Bacterial Cells Exposed to Potassium Permanganate Using Differential Scanning Calorimetry: a Biphasic Dose-Dependent Response to Stress

The DSC technique applied to the study of the toxic impact of permanganate on bacterial cell culture detected the lack of linearity in the dose-response effect. The results were confirmed by the traditional assay of colony forming ability. The changed pattern of thermal spectra of A. oxydans at permanganate treatment, the measurement of the total heat capacity and the temperature of DNP complex demonstrate the possibility to verify the toxic impact in dependence of concentrations value.